Fig. 6.

FGF-2 and EGF effects on PR survival are concentration-dependent. Determination of relative percentages of surviving PRs and treatments were performed as in Figure 5.A, Increasing doses of FGF-2 (1–50 ng/ml) led to increasing survival of PRs up to 20 ng/ml (maximum), whereas further increases in concentration did not stimulate survival (50 ng/ml).B, Increasing doses of EGF (1–50 ng/ml) led to decreasing survival of PRs (maximal at 10 ng/ml). As with FGF-2, higher doses had no effect on PR survival (50 ng/ml). Error bars are SEM (n = 4). *p < 0.05; **p < 0.01; ***p < 0.001.