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BDNF did not affect the electrical excitability of neurons. APV, CNQX, and picrotoxin were used to block the NMDA-, AMPA-, and GABA-induced responses from the input of other cells. Recordings were made in current-clamp mode. A, Shown are the I–V responses recorded from cells both before (A1) and during (A2) BDNF application. B, Shown is the relation between the amplitude of the injected current and the number of action potentials during the 600 msec current pulses.
