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Inhibitors of PI 3 kinase inhibit survival of DRG neurons. A, Wild-type neurons in the presence of 10 ng/ml NGF. n = 5; **p = 0.008; ***p ≤ 0.0001. B, NF1-deficient neurons in the absence of NGF. DMSO is used as a carrier for each of the indicated inhibitors. n = 4; *p = 0.01–0.05; ***p ≤ 0.0003.
