Fig. 4.

Neurological deficit scores in wild-type (Wt) and knock-out mutant mice (Sod2 −/+) at 24 hr ischemia. Small circles andbars are the scores of each animal and mean scores, respectively. *p < 0.05, Mann–WhitneyU test. 0 = No observable neurological deficit, 1 = failed to extend right forepaw, 2 = circled to the right, 3 = fell to the right, 4 = could not walk spontaneously, and 5 = dead. Mean scores of knock-out mice were significantly higher than those of wild-type mice.