Table 1.
Conditions | Growth cone velocity (μm/hr) |
---|---|
Control | 32 ± 41-b |
2 mm EGTA | 33 ± 3 |
5 mm EGTA | 22 ± 31-a |
2 mmNi2+ | 29 ± 7 |
4 mmNi2+ | 23 ± 61-a |
2 mm Co2+ | 33 ± 9 |
4 mmCo2+ | 15 ± 41-a |
2 μm BAPTA | 33 ± 3 |
4 μmBAPTA | nd |
10 μm FPC | 29 ± 4 |
20 μm FPC | 7 ± 31-a |
2 μm KN-62 | 31 ± 3 |
4 μmKN-62 | 13 ± 21-a |
Parallel control experiments were performed for each inhibitor (t test).
Average growth cone velocity of all control experiments. nd, Not determined. 4 μm BAPTA significantly changed growth cone morphology.