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. 1998 Jan 1;18(1):266–283. doi: 10.1523/JNEUROSCI.18-01-00266.1998

Fig. 13.

Fig. 13.

FS interneurons inhibit MS neurons via a fast monosynaptic connection. A, The reversal of the fast monosynaptic connection from an FS interneuron to an MS neuron (49 DIV). Each response is an average from four action potentials.B1, Time course of the synaptic event elicited by a single spike of the FS interneuron. The decay could be fitted to two exponential time courses. B2, The first 25 msec of the postsynaptic response in the MS neurons after a single spike in the FS neurons, an enlargement from B1. The time derivative of the membrane potential (five point smoothing enabled) clearly shows two peaks. C, PSPs in the MS neuron under steady state hyperpolarizing (bottom) and depolarizing (top) conditions. The FS interneuron was depolarized by constant current pulses of 200 msec in duration and fired spikes at high frequencies (dots). The PSPs showed a strong depression during the first 100 msec.