Fig. 2.

Examples of genes acutely induced by SKF38393. Each image is of a coronal rat brain section through the middle striatum, after in situ hybridization with a probe to the gene indicated. All of the brain sections are from animals given unilateral 6-hydroxydopamine lesions and then injected with SKF38393 (5 mg/kg) and killed 2 hr later (except tPA, shown at 4 hr after SKF38393). The lesioned side is shown on the leftin each case. The genes designated “ania-1,” “ania-2,” etc., have no named matches in GenBank. Genes were designated as previously known on the basis of matches to the following accession numbers: homer U92079; CHOP (= GADD153) U36994; krox20 (= egr-2) U78102; preprotachykinin M34184; CREM M60285; fosBX14897; zif268 (= NGFIA/egr-1) M18416; MKP-1 (= CL100)S81478.