Fig. 8.

Effect of CHC on ¹⁴CO₂production from 1-[¹⁴C]acetate in cortical astrocytes and synaptosomes. Both preparations were incubated with 0.2 mm sodium acetate under identical conditions in an oxygenated, glucose-containing, HEPES-buffered HBSS at 37°C for the indicated times. CHC (10 mm) was added to the tissues at the same time as the 1-[¹⁴C]acetate. Data points represent the mean ± SD of four determinations. *Significant differences between CHC and control-treated astrocytes or synaptosomes at the times indicated; p < 0.05. This experiment was repeated two additional times, and the same results were obtained.