Skip to main content
. 1998 Jul 15;18(14):5112–5123. doi: 10.1523/JNEUROSCI.18-14-05112.1998

Fig. 3.

Fig. 3.

The antioxidants vitamin E and NAC promote survival of primary CNS neurons in basal medium. A,B, Dose–response relationships for the effect of vitamin E (A) and NAC (B) on promotion of survival of E18 hippocampal neurons in basal medium (1 d) are shown. The open circle represents survival mediated by 10 μm dipyridamole. Survival data are expressed relative to the number of neurons alive in complete SFM 1 d after plating (arbitrarily set at 100). C, Time course is shown. E18 hippocampal neurons were plated in either complete SFM or basal medium in the presence of the indicated additives. No subsequent addition of these agents was given. D, Antioxidants do not afford additional protection beyond that provided by complete SFM alone. E, Antioxidant effects on survival in basal medium are not additive and fail to increase dipyridamole-promoted survival. All survival data are expressed relative to the number of neurons alive in complete SFM 1 d after plating.