Table 1.
Electrode content | n | GN(control) (nS) | GN (hypoxia) (nS) | ΔGN(%) | ΔIBH (pA) |
---|---|---|---|---|---|
KMeSO4 | 33 | 5.1 ± 0.4 | 9.5 ± 0.9* | 117 ± 15* | −45 ± 6a,* |
KCl | 6 | 5.7 ± 1.4 | 8.6 ± 2.5** | 104 ± 41** | −57 ± 7* |
Cs (fluoride or gluconate) | 20 | 4.2 ± 0.6 | 6.9 ± 0.8* | 91 ± 22* | −57 ± 20** |
EGTA (10 mm) | 11 | 3.8 ± 0.5 | 7.2 ± 1.5** | 97 ± 29** | −35 ± 17*** |
BAPTA (10–30 mm) | 13 | 8.7 ± 0.6 | 16.8 ± 1.2* | 99 ± 16* | −70 ± 20** |
n, Number of cells; GN, input conductance; IBH, baseline holding current.
ΔIBH for KMeSO4-containing electrodes calculated only on 18 neurons clamped at −65 mV.
*p < 0.001; **p < 0.01; ***p < 0.05.