Table 1.
Subject | Species | Sex | Age at beginning of experiment | Experimental procedure1-a | Time until next procedure (or perfusion) | Techniques | Figures |
---|---|---|---|---|---|---|---|
Monkey 1 | M. fascicularis | Male | 11 years | 1. OD—enucleated | 15 weeks | CO | 3 |
OS—normal | |||||||
Monkey 2 | M. mulatta | Female | 15 years | 1. OD—sutured | 29 weeks | CO | 4, 7, 8, 9 |
2. OS—focal laser lesion, temporal retina | 9 weeks | ||||||
Monkey 3 | M. mulatta | Male | 12 weeks | 1. OD—sutured | 12 months | CO, autoradiography | 5 |
2. OS—normal, [3H]proline injection | 9 d | ||||||
Monkey 4 | M. mulatta | Female | 5 weeks | 1. OD—sutured 2. OS—normal, [3H]proline injection | 24 months 9 d | CO, autoradiography, Luxol fast blue, Nissl | 6 |
Monkey 5 | M. mulatta | Female | 3 weeks | 1. OD—sutured 2. OS—normal, [3H]proline injection | 24 months 9 d | CO, autoradiography, Luxol fast blue, Nissl | Not illustrated |
Monkey 6 | M. mulatta | Female | 9 years | 1. OD—sutured | 33 weeks | CO, anti-Zif268 | Not illustrated |
2. OS—focal laser lesion, temporal retina | 6 weeks | ||||||
Monkey 7 | M. fascicularis | Male | 10 years | 1. OS—focal laser lesion, temporal retina | 7 weeks | CO, anti-Zif268 | 10–12 |
2. OD—enucleated | 4 hr | ||||||
Monkey 8 | M. fascicularis | Male | 8 years | 1. OD—enucleated | 11 months | CO, autoradiography | 13–16 |
2. OS—focal laser lesion, temporal retina | 14 weeks | ||||||
3. OS—focal laser lesion, nasal retina | 3 weeks | ||||||
4. OS—[3H]proline injection | 9 d | ||||||
Human subject | Male | 67 years | OD—normal | 4 years | CO | 17–19 | |
OS—macular degeneration |
OD, Right eye; OS, left eye.