Fig. 11.

Computer simulations of the effects of a Kv3.1-like potassium conductance on action potential repolarization in inferior colliculus neurons. Inactivating (A) and noninactivating (B) potassium currents of the model cells were fit closely to the current traces shown in Figure3B,C. C, D, Action potentials were simulated in response to 20 pA current pulses in model cells with varying levels of the high-threshold noninactivating current. Thetrace in D represents a 2.2-fold increase in the conductance of the noninactivating potassium current over that in C, with no changes in other parameters. The increase in this current enhanced the AHP.