Fig. 3.

Effects of pentobarbital (left, 33 mg/kg; right, 27.4 mg/kg) on somatosensory evoked firing of two striatal neurons in chronically implanted animals. In eachcolumn, the raster and PSTH below it display firing of one neuron before (top), during (middle), and after partial or complete recovery (bottom) from pentobarbital anesthesia.Arrows at time 0 indicate the approximate stimulus onset. Left, Neuron responsive to passive manipulation of the contralateral forelimb in rat C44. Evoked discharges per stimulus were 17 (Pre), 0.17 (Pentobarb.), and 29 (Recovery). The evoked response epoch was time 0 to 1.0 sec; the baseline epoch was −0.6 to −0.1 sec. The stimulus duration ranged between 0.5 and 1.0 sec. The pentobarbital PSTH was taken 40 min after injection. The number of sweeps in each condition was 53. Right, Neuron with receptive field on the contralateral, dorsal trunk between the forelimb and hindlimb in rat C45. Evoked discharges per stimulus were 4.7 (Pre), 0.17 (Pentobarb.), and 1.8 (Recovery). The pentobarbital PSTH was taken 20 min after injection. The evoked response epoch was time 0 to 0.35 sec; the baseline epoch was −0.4 to −0.1 sec. The stimulus duration ranged between 0.1 and 0.3 sec. The number of sweeps in each condition was 150. Inset, Representative neural waveform in this and subsequent figures was maintained throughout the experiment, indicating no change in electrode position. Waveform calibration: 0.2 mV, 1.0 msec. Location of each neuron: 0.8–1.0 mm (left) and 0.4–0.5 mm (right) inside the dorsolateral edge of the striatum, as in the electrode tracks at the bottom of Figure 2.