Figure 2.

Quantitative analysis of 17β-estradiol effects on the global morphology of layer III neurons in area 46. There were no 17β-estradiol-induced changes in total dendritic length (a) and total branch number (b) observed. Sholl analysis showed that long-term cyclic 17β-estradiol treatment had no effects on the degree of branching of layer III neuron in area 46 (c–f). A two-way mixed model for repeated measures was used for testing the treatment effect, both overall and for each individual radial distance point from the soma. Error bars represent SEM.