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. 1997 Jan 1;17(1):125–139. doi: 10.1523/JNEUROSCI.17-01-00125.1997

Fig. 4.

Fig. 4.

In situ hybridization and IHC of PDGF-αR on P15 brain and spinal cord tissue sections. Expression of PDGF-αR transcripts in the cerebral cortex (A). High-magnification view of the hybridization signal showing the localization of PDGF-αR mRNA in the soma of cortical neurons (arrows in B). Detection of PDGF-αR transcripts in the hippocampus (C) and in motoneurons (arrowheads) of the spinal cord (D). Longitudinal spinal cord section, hybridized with the digoxigenin-labeled antisense probe complementary to murine PDGF-αR, showing the localization of the transcripts in motoneurons (arrowheads) and oligodendrocyte precursors (arrows; E). Adjacent section immunolabeled with the anti-PDGF-αR antibody (F). Note that motoneurons and immature cells of the oligodendrocyte lineage express PDGF-αR transcripts and protein.CA1, CA3, Hippocampal fields;DG, dentate gyrus. A–D, E, Bright-field and phase-contrast; F, indirect immunofluorescence. Magnification: A, C, E, F, 124×; B, D, 248×.