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Basal synaptic transmission is unaffected by GRGDSP. Field EPSPs were elicited by single stimulation pulses delivered to the Schaffer commissurals of four slices, and the initial slope was measured. The plotted data are group means (± SD) represented as the percent of the initial baseline established over an 18 min period before a 55 min infusion of GRGDSP (0.5 mm). Responses were continually recorded during washout of the peptide.
