Table 1.
Peptide (n) | Baseline response characteristics (mean ± SEM) | |||||
---|---|---|---|---|---|---|
Initial slope | Amplitude | Area | Riset1/2 | Decayt1/2 | ½ width | |
Control (16) | 0.60 ± 0.02 | 1.29 ± 0.04 | 8.25 ± 0.37 | 1.95 ± 0.06 | 3.96 ± 0.14 | 5.91 ± 0.23 |
(−mV · ms−1) | (−mV) | (mV · msec) | (msec) | (msec) | (msec) | |
GAVSTA (16) | 0.59 ± 0.03 | 1.38 ± 0.05 | 8.94 ± 0.40 | 2.09 ± 0.05 | 3.86 ± 0.15 | 6.07 ± 0.20 |
Field EPSP parameters were assessed during the 1–2 min period immediately before the application of TBS. Peptides were infused for 50–90 min before baseline response characteristics were measured. Control: 2 mm ASG or 0.8 mm GRADSP, measured from 16 pathways. GAVSTA: 0.8 mm peptide in 16 pathways.