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The inward rectifier “paces” GGPs.A, Spontaneous GABAergic bursts in a CA3 pyramidal neuron at P3 (top trace) and in a hilar interneuron at P4 (bottom trace). Resting membrane potentials are −68 mV in the pyramidal cell and −59 mV in the hilar interneurons. Octanol slightly depolarized the membrane and reversibly inhibited GGPs. Cs+ blocked GGPs as well. B, Time course of the GGPs frequency for the cells shown in A before, during (see bars in inset), and after application of drugs.
