Table 2.
Open field activity and rotating rod learning of wild-type and α6 −/− mice
| n | Open field activity/5 min | ||||||
|---|---|---|---|---|---|---|---|
| Number of crossings | Number of fecal boli | Number of rearings | |||||
| +/+ | 10 | 96 ± 5 | 3.3 ± 0.7 | 6.7 ± 1.5 | |||
| −/− | 10 | 84 ± 18 | 3.2 ± 0.5 | 5.2 ± 1.1 | |||
| n | Rotarod performance: seconds on the rod per 180 sec/(percent of animals staying for 180 sec) | ||||||
|---|---|---|---|---|---|---|---|
| Trial 1 | Trial 2 | Trial 3 | Trial 4 | Trial 5 | Trial 6 | ||
| +/+ | 15 | 114 ± 11 (20%) | 147 ± 9 (40%) | 160 ± 11 (67%) | 179 ± 1 (87%) | 179 ± 1 (87%) | 180 ± 0 (100%) |
| −/− | 14 | 144 ± 11 (43%) | 148 ± 12 (57%) | 167 ± 8 (79%) | 176 ± 3 (86%) | 176 ± 4 (93%) | 180 ± 0 (100%) |
Results are given as means ± SEM. No statistically significant differences (p < 0.05; Student’s ttest and repeated measures ANOVA). The Rotarod learning test was repeated with another batch of mice with similar results.