Fig. 3.
Recordings from patches containing single Ls channels showed increased activity after exposure to 8-CPT-cAMP.A, Two sets of five consecutive sweeps of Ls channel activity from a control patch (left) and one that had been pretreated with 1 mm 8-CPT-cAMP (right). Both patches contain only one Ls channel.B, Plot of po from control patches (n = 10) and those treated with 8-CPT-cAMP (n = 11). C, Plot of null sweep probability from control patches and those treated with 8-CPT-cAMP. In both B and C, asterisksindicate significant difference (p < 0.001). D, Open time distributions from test pulses to +20 mV from a holding potential at −40 mV. Data are summed from all recordings. E, Open time distributions from patches exposed to 1 mm 8-CPT-cAMP. Voltages are the same as inD. Data are summed from all recordings.