Fig. 5.

Effect of 21 consecutive daily flurothyl-induced generalized seizures on the GST and the generalized seizure phenotype. Points represent the mean GST ± SEM of six animals. Thebars represent the proportion of generalized seizures that were “brainstem seizures” within a defined “bin.” A bin is composed of the total number of seizures in regular three trial intervals. Continuing stimulation for 2 weeks beyond the first eight trials did not significantly alter the proportion of mice expressing “brainstem seizures” (cf. Table 2).