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. 1997 Jul 15;17(14):5610–5621. doi: 10.1523/JNEUROSCI.17-14-05610.1997

Fig. 3.

Fig. 3.

Persistent and transient components of the gIPSP.A, The LP neuron was held at −50 mV, and a sequence of voltage steps, to voltages ranging from −45 to 0 mV, was applied. The amplitude of the gIPSP in the PD cell was measured at the peak and at the end of the pulse (1.75 sec). The initial membrane potential of the PD neuron was −49 mV. Vertical bar, 3.2 mV (PD) and 50 mV (LP).B, The amplitudes at the peak (open circles) and at 1.75 sec (filled circles) of the traces in A are plotted against the presynaptic potential. The amplitude measured at 1.75 sec (the persistent component) was subtracted from the peak amplitude to obtain the transient component (double-headed arrow).C, Both components were normalized to their respective values at +10 mV to obtain the I/O curves (mean ± SEM). The I/O curve of the transient component (open triangles) had a steeper slope and a more hyperpolarized midpoint than that of the persistent component (filled circles).