Fig 1. Schematic overview of the NID CDEs’s structure.

13 ItemGroups of the NID CDEs in chronological order for obtaining a patient’s medical history. Starting with documentation of diagnosis and confirmation of diagnoses (CSF analysis), followed by disease activity (disease progress, relapses and EDSS), current and previous disease modifying therapy and imaging results (MRI results). “Other medical information” provides the possibility of recording further medical information, such as secondary diagnoses, concomitant medications or findings in physical examination.