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. 2019 Oct 15;14(10):e0222875. doi: 10.1371/journal.pone.0222875

Table 3. Incidences and hazard ratios of bladder cancer based on a Cox proportional hazard regression stratified by age, sex, region, comorbidity, follow-up duration.

BD Comparison HR (95% CI)
Event no Incidence Event no Incidence Crude Adjusted
Age, year
 18–64 7 1.84 9 0.57 3.20 (1.19–8.60)* 3.33 (1.24–8.95)*
 > = 65 30 3.82 49 1.53 2.49 (1.58–3.91)*** 2.52 (1.60–3.96)***
Sex
 Female 3 0.95 16 1.25 (0.22–2.61) 0.81 (0.24–2.79)
 Male 34 3.99 42 1.20 3.31 (2.10–5.20)*** 3.32 (2.11–5.22)***
Comorbidity status
 No 17 4.01 18 0.88 4.52 (2.33–8.77)*** 4.86 (2.50–9.44)***
 Yes 20 2.69 40 1.47 1.83 (1.07–3.13)* 1.78 (1.04–3.04)*
Follow-up duration, years
 <5 25 3.03 44 1.32 2.30 (1.41–3.75)*** 2.31 (1.42–3.78)***
 ≧5 12 3.51 14 0.97 3.57 (1.65–7.73)** 3.60 (1.66–7.78)**

Models adjusted for age and CKD

Incidence, per 1000 person-years

* p < 0.05,

** p<0.01,

*** p < 0.001

BD: bladder diverticulum

Interaction p < 0.05