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. 2019 Oct 15;14(10):e0222886. doi: 10.1371/journal.pone.0222886

Table 2. Characteristics of participants without overt HF (sample 1).

CHD (N = 185) Metabolic Syndrome (N = 1595) Hypertension (N = 482) Obesity (N = 383) Referent group (N = 2891)
Age at Index Exam, years 68.3 (9.6) 56.6 (14.0) 56.8 (14.1) 44.4 (11.8) 43.3 (12.7)
Women, N (%) 65 (35%) 732 (46%) 253 (52%) 215 (56%) 1745 (60%)
BMI, kg/m2 28.9 (4.8) 30.4 (5.1) 26.2 (4.4) 33.3 (3.3) 24.1 (2.9)
Obesity 69 (37%) 733 (46%) 76 (16%) 383 (100%) 0 (0%)
Systolic blood pressure, mm Hg 129 (16) 130 (16) 137 (16) 116 (9) 112 (11)
Diastolic blood pressure, mm Hg 70 (9) 78 (11) 82 (11) 75 (7) 72 (8)
Hypertension treatment, N (%) 138 (75%) 742 (47%) 272 (56%) 0 (0%) 0 (0%)
Hypertension, N (%) 146 (79%) 976 (61%) 482 (100%) 0 (0%) 0 (0%)
Diabetes, N (%) 49 (26%) 244 (15%) 0 (0%) (0%) (0%)
Current smoker, N (%) 16 (9%) 198 (12%) 52 (11%) 39 (10%) 411 (14%)
Coronary heart disease, N (%) 185 (100%) 0 (0%) 0 (0%) 0 (0%) 0 (0%)
Metabolic syndrome, N (%) 146 (79%) 100% 0 (0%) 0 (0%) 0 (0%)
Micro albuminuria, N (%) 28 (15%) 100 (6%) 28 (6%) 11 (3%) 56 (2%)
Estimated GFR (ml/min/1.73 m2) 74.4 (17.2) 88.3 (19.0) 87.9 (18.5) 100.5 (15.1) 99.7 (15.9)
Chronic kidney disease, N (%) 52 (28%) 203 (13%) 56 (12%) 13 (4%) 86 (3%)
Atrial fibrillation 27 (15%) 32 (2%) 6 (1%) 3 (1%) 19 (1%)
COPD* 16 (12%) 65 (8%) 18 (7%) 5 (6%) 38 (7%)

* Percentages are calculated based on the sample where data were available (only in the Offspring sample, at examination cycle 8).