Table 1.
Raw data from all genetic populationsa
| Strain | All mice | Female mice | Male mice | ||||||
|---|---|---|---|---|---|---|---|---|---|
| n | BL | PS | n | BL | PS | n | BL | PS | |
| B6 | 13 | 19.1 ± 1.2 | 46.5 ± 4.3 | 7 | 20.5 ± 1.4 | 46.7 ± 5.0 | 6 | 17.5 ± 1.9 | 46.2 ± 7.7 |
| D2 | 17 | 24.3 ± 1.6 | 42.5 ± 3.9 | 8 | 22.2 ± 2.4 | 39.1 ± 4.5 | 9 | 26.1 ± 2.0 | 45.6 ± 6.3 |
| (B6xD2)F1 | 26 | 18.0 ± 0.9 | 38.5 ± 3.6 | 8 | 18.8 ± 2.2 | 37.5 ± 6.7 | 18 | 17.7 ± 0.8 | 39.0 ± 4.4 |
| BXD-1 | 14 | 22.6 ± 0.9 | 58.2 ± 1.2 | 7 | 21.4 ± 0.6 | 58.1 ± 1.9 | 7 | 23.7 ± 1.7 | 58.3 ± 1.7 |
| BXD-2 | 15 | 19.4 ± 1.6 | 32.5 ± 3.8 | 7 | 20.0 ± 2.4 | 29.6 ± 3.2 | 8 | 18.9 ± 2.1 | 35.1 ± 6.6 |
| BXD-5 | 15 | 18.3 ± 1.7 | 48.2 ± 4.8 | 8 | 17.1 ± 2.3 | 51.6 ± 5.9 | 7 | 19.8 ± 2.5 | 44.2 ± 8.0 |
| BXD-6 | 18 | 19.8 ± 1.8 | 50.6 ± 3.0 | 9 | 19.9 ± 2.9 | 51.3 ± 4.4 | 9 | 19.7 ± 2.2 | 49.9 ± 4.4 |
| BXD-8 | 17 | 28.6 ± 2.1 | 52.1 ± 3.5 | 10 | 27.3 ± 2.8 | 54.2 ± 3.3 | 7 | 30.5 ± 3.2 | 49.1 ± 7.2 |
| BXD-9 | 12 | 19.8 ± 2.1 | 55.5 ± 3.1 | 8 | 16.3 ± 2.2 | 53.2 ± 4.4 | 4 | 26.6 ± 1.9 | 60 ± 0 |
| BXD-11 | 16 | 18.1 ± 1.7 | 52.5 ± 3.6 | 9 | 14.9 ± 1.7 | 54.5 ± 3.8 | 7 | 22.1 ± 2.6 | 49.8 ± 7.0 |
| BXD-12 | 14 | 24.5 ± 1.7 | 55.1 ± 2.1 | 7 | 26.0 ± 2.8 | 55.4 ± 3.3 | 7 | 23.0 ± 2.1 | 54.7 ± 2.7 |
| BXD-13 | 14 | 23.9 ± 2.3 | 60 ± 0 | 7 | 21.3 ± 2.2 | 60 ± 0 | 7 | 26.6 ± 4.0 | 60 ± 0 |
| BXD-14 | 13 | 24.6 ± 2.2 | 35.8 ± 4.6 | 6 | 18.7 ± 1.2 | 30.0 ± 7.5 | 7 | 29.7 ± 2.8 | 40.9 ± 5.5 |
| BXD-15 | 19 | 18.3 ± 1.6 | 43.9 ± 3.6 | 10 | 16.5 ± 2.7 | 39.4 ± 5.7 | 9 | 20.3 ± 1.6 | 48.8 ± 3.8 |
| BXD-16 | 15 | 15.1 ± 1.5 | 49.6 ± 3.6 | 8 | 15.9 ± 0.6 | 50.2 ± 5.1 | 7 | 14.1 ± 3.2 | 48.8 ± 5.5 |
| BXD-18 | 18 | 25.9 ± 1.7 | 51.5 ± 3.0 | 7 | 23.6 ± 2.7 | 47.7 ± 6.2 | 11 | 27.4 ± 2.1 | 53.9 ± 3.1 |
| BXD-19 | 17 | 16.1 ± 1.5 | 33.1 ± 3.1 | 9 | 15.2 ± 2.3 | 34.0 ± 4.4 | 8 | 17.0 ± 1.9 | 32.1 ± 4.5 |
| BXD-21 | 14 | 20.9 ± 1.5 | 56.4 ± 3.2 | 7 | 20.7 ± 2.7 | 60 ± 0 | 7 | 21.0 ± 1.4 | 52.7 ± 6.3 |
| BXD-22 | 9 | 24.6 ± 3.2 | 44.2 ± 6.5 | 3 | 17.3 ± 5.5 | 31.7 ± 14.2 | 6 | 28.2 ± 3.2 | 50.5 ± 6.0 |
| BXD-23 | 16 | 15.9 ± 2.1 | 37.0 ± 4.0 | 8 | 13.5 ± 2.1 | 31.5 ± 5.5 | 8 | 18.2 ± 3.5 | 42.6 ± 5.5 |
| BXD-25 | 18 | 24.2 ± 2.0 | 54.9 ± 2.6 | 8 | 19.5 ± 2.1 | 57.1 ± 2.9 | 10 | 27.9 ± 2.8 | 53.2 ± 4.1 |
| BXD-27 | 18 | 20.4 ± 1.8 | 54.5 ± 2.3 | 9 | 21.3 ± 1.9 | 60 ± 0 | 9 | 19.5 ± 3.3 | 48.9 ± 3.8 |
| BXD-28 | 18 | 18.3 ± 1.3 | 50.7 ± 3.3 | 9 | 17.4 ± 1.7 | 47.1 ± 4.4 | 9 | 19.2 ± 1.9 | 54.3 ± 4.8 |
| BXD-29 | 19 | 17.9 ± 1.3 | 33.4 ± 4.0 | 9 | 16.9 ± 1.9 | 33.4 ± 5.2 | 10 | 18.8 ± 1.8 | 33.5 ± 6.2 |
| BXD-30 | 14 | 18.9 ± 1.1 | 34.2 ± 5.0 | 7 | 18.0 ± 1.6 | 28.0 ± 6.1 | 7 | 19.9 ± 1.6 | 40.1 ± 7.7 |
| BXD-31 | 16 | 13.0 ± 1.1 | 24.6 ± 4.2 | 7 | 12.6 ± 1.3 | 14.7 ± 2.4 | 9 | 13.3 ± 1.7 | 32.3 ± 6.2 |
| BXD-32 | 21 | 13.6 ± 1.2 | 41.4 ± 3.3 | 10 | 12.4 ± 1.3 | 44.4 ± 4.6 | 11 | 14.7 ± 2.0 | 38.6 ± 4.8 |
The 54°C hot-plate latencies (in seconds) of all genetic populations immediately before [baseline (BL)] and 2 min after [post-swim (PS)] 3 min forced swims in 15°C water. Analgesic magnitudes expressed as %MPE = [(PS − BL)/(60 − BL)] × 100 were calculated from these data (in BXD strains only) for purposes of QTL analysis (see Fig. 1).