Table 2.

Correlation coefficients (r) of significantly associated marker loci (p < 0.01 for all mice) for 15°C swim SIA in 24 BXD RI strains^a

Marker	Location	r	Present status
Ms15-6	Chromosome 5; 42 cM	−0.6182-160	Disconfirmed
Brp1	Chromosome 6; 32 cM	0.559*	Putative2-b
D8Rik78	Chromosome 8; 55–56 cM	0.6432-165	Confirmed for females only2-b
D11Ncvs69	Chromosome 11; 16 cM	−0.5752-160	Disconfirmed
Cbg	Chromosome 12; 51 cM	0.524*	Disconfirmed
D17Mit22	Chromosome 17; 10 cM	0.6302-160	Disconfirmed

^F2-aOnly the marker showing the highest correlation (for all mice) among several closely linked markers is shown. The centiMorgan (cM) locations represent estimated map distances from the centromere (Mouse Genome Database athttp://www.informatics.jax.org/mgd.html). For all marker loci, a genotypic score of 0 was assigned to the B6 allele and a score of 1 to the D2 allele; negative correlations thus indicate that the B6 allele at that locus is associated with higher SIA magnitude. Attempts were made to confirm all six QTL regions in a (B6xD2)F₂ hybrid population; four of these attempts were unsuccessful, indicating that the loci were likely false positives.

^F2-bSee Table 3 for details.

^*p < 0.01;

F2-160: p < 0.005;

F2-165: p < 0.0001.