Fig. 2.

Properties of postsynaptic current responses evoked by the standard HFS train under voltage-clamp conditions.A, Specimen recordings of currents. Vertical bars indicate the timing of I–V samples.B, Consecutive I–V curves taken at 0.2 sec intervals from the family of recordings in A, with the onset of the HFS train assigned time 0. To facilitate visual inspection, the curves related to 0–1.0 sec (top panel) and 1.0–2.0 sec (bottom panel) are given separately, with a different scale for current amplitudes. C, Change in the reversal potential of the hIPSC/GDPSC as a function of time sampled at 0.1 sec intervals (open symbols represent extrapolated values; see B). Note that from 1.5 to 2.0 sec, theI–V slope is too shallow to yield a meaningful extrapolation.