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. 2019 Oct 15;14(10):e0223703. doi: 10.1371/journal.pone.0223703

Table 1. Baseline characteristics of patients with AAV.

Total Renal Non-renal P value
(Renal vs Non-renal)
Number 51 41 10
Age (years) 67.6 ± 1.8 68.6 ± 1.9 63.7 ± 5.3 0.4
Sex (M/F) 24/27 20/21 4/6
MPA/GPA/EPGA 43/6/2 35/6/0 8/0/2
MPO+/PR3+ 46/5 36/5 10/0
Onset 40 30 10
Focal/Crescentic/
Mixed/Sclerotic
4/4/5/1 4/4/5/1 -
Relapse 5 5 -
Remission 6 6 -
CRP (mg/dl) 6.9 ± 0.7 7.1 ± 0.8 6.2 ± 1.4 0.61
sCr (mg/dl) 2.05 ± 0.3 2.39 ± 0.35 0.63 ± 0.05 <0.001
eGFR
(mL/min/1.73m2)
44.9 ± 4.2 34.5 ± 3.3 87.6 ± 7.5 <0.001
U-Pro/Cr (g/gCr) 1.08 ± 0.18 1.32 ± 0.21 0.16 ± 0.02 <0.001

MPO: myeloperoxidase-ANCA. PR3: proteinase3-ANCA. CRP: C-reactive protein. L-FABP: L-type fatty acid-binding protein. NAG: N-acetyl-beta-glucosaminidase. MPA: microscopic polyangiitis. GPA: granulomatosis with polyangiitis. EPGA: eosinophilic granulomatosis with polyangiitis.