Table 3.
Ten-question Physical Functioning Questionnaire Scores At Visits 1 And 2, And Change From Baseline (full Analysis Set) (N=7218)
| PF-10 score | |
|---|---|
| Visit 1 (baseline) | |
| Mean (SD) | 46.1 (23.3) |
| Median (min–max) 95% CI |
45.0 (0–100) 45.6, 46.7 |
| Visit 2 (after approximately 6 weeks) | |
| Mean (SD) | 62.7 (21.5) |
| Median (min–max) | 65.0 (0–100) |
| 95% CI | 62.2, 63.2 |
| Therapeutic success (proportion of patients with a ≥10-point increase in PF-10 after approx. 6 weeks) | |
| Overall | |
| n (%) | 4891 (67.8) |
| 95% CI | 66.7, 68.8 |
| GOLD Aa | |
| n (%) | 766 (49.3) |
| 95% CI | 46.8, 51.8 |
| GOLD Ba | |
| n (%) | 2515 (70.9) |
| 95% CI | 69.4, 72.4 |
| GOLD Ca | |
| n (%) | 209 (58.5) |
| 95% CI | 53.2, 63.7 |
| GOLD Da | |
| n (%) | 1401 (79.7) |
| 95% CI | 77.7, 81.6 |
Notes: aGOLD subgroup according to 2017 classification, based on symptoms and exacerbations only.
Abbreviation: PF-10, 10-question Physical Functioning Questionnaire.