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. 2019 Jul 18;13(11):2817–2833. doi: 10.1038/s41396-019-0472-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Virus/host dynamics in the large size class. Viruses and hosts are annotated as the closest reference available in our database, as determined by LPI. Library normalized expression of ORFs classified as ssRNA (yellow), dsRNA (green), and dsDNA (pink) viruses and their putative hosts by LPI are shown. Putative host expression is represented by solid lines and corresponds to left y-axes; virus expression is represented by dashed lines and corresponds to the right y-axes. Night hours are shaded in gray. Note that OtV2 infects RCC393, an Ostreococcus Clade OII species, not O. tauri. OtV2 was isolated against Ostreococcus Clade OII isolate RCC393 [94] which has 99% 18S rDNA identity to the genome sequenced Clade OII isolate RCC809 used in our mapping analysis. Likewise, the M. commoda-like reovirus infects the strain LAC38, which was initially misreported as being M. pusilla and has been renamed here according to proper species assignment of the host [87]. Interestingly, while picoprasinophyte populations mapping most closely to Micromonas pusilla were coactive with a dsDNA virus, populations mapping most closely to Micromonas commoda (RCC299) were coactive with a dsRNA virus [87, 95]