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. 2019 Oct 9;7:411. doi: 10.3389/fped.2019.00411

Table 3.

The associators of elevated blood pressure in children and adolescents aged 7–18 years in China, 2014.

Model 1 Model 2 Model 3
Covariates OR 95% CI of OR P OR 95% CI of OR P OR 95% CI of OR P
Boys (ref = girls) 2.406 1.887 3.069 <0.001 2.377 1.858 3.041 <0.001 2.497 1.926 3.239 <0.001
Age (every 2 years increase) 1.497 1.382 1.621 <0.001 1.535 1.414 1.666 <0.001 1.604 1.463 1.760 <0.001
Shaanxi Province (ref = Hainan) 2.239 1.652 3.033 <0.001 2.553 1.867 3.490 <0.001 2.871 1.962 4.202 <0.001
Li ethnicity (ref = Han) 1.105 0.848 1.440 0.458 1.204 0.919 1.578 0.177 0.812 0.601 1.096 0.174
Urban (ref = rural) 1.208 0.939 1.556 0.142 1.124 0.870 1.451 0.101 0.779 0.580 1.045 0.096
Positive Family history of HTN (ref = negative) 1.002 0.773 1.298 0.989 0.955 0.736 1.241 0.733 1.037 0.790 1.362 0.794
Thinness (ref = normal weight) 0.700 0.469 1.046 0.082 0.700 0.469 1.046 0.082 0.648 0.428 0.981 0.040
Overweight/obesity (ref = normal weight) 2.128 1.394 3.248 <0.001 2.128 1.394 3.248 <0.001 2.671 1.679 4.251 <0.001
Body fat percentage (every 5% increase)* 1.114 1.030 1.206 0.007 1.114 1.030 1.206 0.007 1.150 1.054 1.255 0.002
Serum calcium level (ref = low) 1.665 1.300 2.133 <0.001 1.640 1.279 2.103 <0.001 1.508 1.170 1.943 0.001
Regular physical exercise (ref = never) 1.077 0.685 1.693 0.747 1.103 0.700 1.737 0.673 1.189 0.747 1.892 0.464
Occasionally physical exercise (ref = never) 1.354 0.895 2.051 0.152 1.403 0.924 2.129 0.112 1.238 0.810 1.893 0.325
Dyslipidemia (ref = no dyslipidemia) 1.119 0.838 1.495 0.446 1.040 0.775 1.395 0.794 1.107 0.820 1.494 0.506

Elevated blood pressure was defined as pre-hypertension or hypertension. HTN, hypertension. CI, confidence interval. Model 1: adjusted for age and sex; model 2: further adjusted for BMI (categorial) based on model 1. Model 3: further adjusted for urbanization, study sites, ethnicity, family history of hypertension, serum calcium level, physical exercises, and dyslipidemia based on model 2.

*

The adjusted covariates for model 2 and model 3 excluded BMI due to its high correlation (the Pearson correlation coefficient = 0.76) with body fat percentage. The classification of low or high in serum calcium level was based on its median value in the overall participants, which was 2.47 mmol/L.