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. 2019 Oct 9;10:690. doi: 10.3389/fendo.2019.00690

Figure 3.

Figure 3

Mitochondrial generation of ROS. Complexes I, II, and III (complexes located on electron transport chain) play a pivotal role in the generation of ROS during the process of oxidative phosphorylation. The increased ROS regulated cancer progression, angiogenesis, metastasis, and survival.