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Predicted glycosylation sites generated by somatic hypermutation in V genes and their structural location. (A) SHM hotspots for glycosylation in IGHV1-69, IGHV3-11, and IGHV4-39 genes. (B) A structural demo (PDBID: 1dn0) shows the predicted glycosylation hotspots to be surface-exposed, indicating accessibly for post-translational modification.
