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CNTF decreases the activity of the glycolytic enzyme LDH but does not affect oxidative phosphorylation in vivo. A, LDH activity is slightly decreased by 11% in the striatum injected with lenti-CNTF, as evidenced on brain sections processed for LDH histochemistry. B, CNTF overexpression has no effect on striatal oxidative metabolism as shown by COX histochemistry. Data are expressed as mean ± SEM; **p < 0.01; Student's paired t test; n = 6 per group.
