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. 2019 Oct 9;9:921. doi: 10.3389/fonc.2019.00921

Table 3.

Regression model analysis for diagnosis testing.

Stages Variable Univariate analysis Multiivariate analysis
B OR (95%CI) P-value B OR (95%CI) P-value
All CRC CXCL7 2.763 15.850 (9.957–25.231) <0.001 2.156 8.637 (5.198–14.352) <0.001
CEA 0.480 1.616 (1.420–1.840) <0.001 0.314 1.369 (1.192–1.573) <0.001
CA125 0.078 1.081 (1.058–1.104) <0.001 0.062 1.064 (1.032–1.097) <0.001
CA19-9 0.072 1.074 (1.053–1.096) <0.001 0.057 1.059 (1.031–1.087) <0.001
Stage I–II CXCL7 2.234 9.333 (5.790–15.044) <0.001 1.796 6.824 (3.570–10.166) <0.001
CEA 0.453 1.572 (1.351–1.831) <0.001 0.309 1.363 (1.164–1.595) <0.001
CA125 0.075 1.077 (1.052–1.103) <0.001 0.065 1.067 (1.003–1.101) <0.001
CA19-9 0.061 1.063 (1.040–1.086) <0.001 0.054 1.056 (1.026–1.086) <0.001
Male subgroup CXCL7 3.875 48.164 (21.716–106.825) <0.001 3.206 24.676 (10.471–58.151) <0.001
CEA 0.542 1.720 (1.438–2.056) <0.001 0.360 1.433 (1.122–1.830) 0.004
CA125 0.078 1.081 (1.053–1.111) <0.001 0.056 1.058 (1.013–1.105) 0.011
CA19-9 0.066 1.068 (1.043–1.094) <0.001 0.040 1.041 (1.006–1.077) 0.020
Female subgroup CXCL7 1.711 5.533 (3.097–9.883) <0.001 1.158 3.185 (1.614–6.285) 0.001
CEA 0.405 1.499 (1.256–1.789) <0.001 0.296 1.345 (1.146–1.578) <0.001
CA125 0.076 1.079 (1.042–1.116) <0.001 0.071 1.075 (1.026–1.12) 0.002
CA19-9 0.083 1.087 (1.047–1.128) <0.001 0.084 1.088 (1.036–1.142) 0.001