Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The inclusion of HCDPs filtered by gene co-expression (GCE-HCDP) to generate extended gene sets led to an overall improved target prioritisation performance when compared with the inclusion of unfiltered HCDPs and un-extended gene sets.
| a. Average F1-score | ||
| Original test | 0.211 | |
| +HCDP | 0.327 | |
| +Co-exp-HCDP | 0.341 | |
| b. T-test | ||
| Original test | +HCDP | |
| +HCDP | 5.77×10−18 | |
| +Co-exp-HCDP | 5.93×10−22 | 6.14×10−20 |
