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. 2019 Oct 11;12:8421–8436. doi: 10.2147/OTT.S221305

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© 2019 Yu and Hann.

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Human GAS5 gene and mature lncRNA GAS5 structure. Blue boxes represent the 12 exons and green lines represent the 11 introns of human GAS5 gene, and red boxes represent the snoRNA sequences present within 10 of its introns. Human GAS5 gene is located at 1q25.1 and comprises 12 exons and 11 introns. GAS5 transcribes to two types of mature lncRNA, namely GAS5a and GAS5b, due to the presence of alternative 5ʹ-splice donor sites in exon 7.