Table 2.
The Effects Of GAS5 On Phenotype In Human Cancer
| Phenotype | Inhibition Or Promotion | Cancer Type |
|---|---|---|
| Proliferation | Inhibited | LC, BC, EC, GC, CRC, HCC, PC, CC, OC, PCa, RCC, BCa, glioma, OSCC, SC, melanoma, osteosarcoma |
| Apoptosis | Promoted | LC, BC, EC, GC, CRC, HCC, PC, ECa, CC, OC, RCC, BCa, glioma, SC, melanoma |
| Cell cycle arrest | Promoted | BC, EC, GC, CRC, PC, CC, PCa, RCC, BCa, melanoma |
| Migration | Inhibited | LC, BC, CRC, HCC, PC, CC, OC, RCC, glioma, OSCC, melanoma, osteosarcoma |
| Invasion | Inhibited | LC, EC, CRC, HCC, PC, CC, OC, RCC, glioma, OSCC, melanoma, osteosarcoma |
| EMT | Inhibited | PC, OSCC |
| Radio and drug therapy sensitivity | Promoted | LC, BC, GC, PC, CC, PCa, RCC, BCa, glioma |
| Angiogenesis | Inhibited | CRC |
Abbreviations: LC, lung cancer; BC, breast cancer; EC, esophageal carcinoma; GC, gastric cancer; CRC, colorectal cancer; HCC, hepatocellular carcinoma; PC, pancreatic cancer; ECa, endometrial cancer; CC, cervical cancer; OC, ovarian cancer; PCa, prostate cancer; RCC, renal cell carcinoma; BCa, bladder cancer; GBM, glioblastoma; OSCC, oral squamous cell carcinoma; TC, thyroid cancer; SC, skin cancer.