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. 2019 Oct 8;10:83. doi: 10.1186/s40104-019-0386-x

Table 4.

Gastrointestinal morphometrics and ex-vivo small intestinal permeability. Data are expressed as LSmeans (n = 15 per treatment)

Parameter Lc-AXOS CELL Pooled P-value
No Yes No Yes SEM lc-AXOS CELL
Absolute metrics
 Stomach weight, g 45 44 43 45 2.0 0.606 0.572
 Small intestine length, cma 746 771 728 789 23.7 0.408 0.080
 Small intestine weight, g a 219 222 219 222 9.5 0.746 0.789
 Large intestine length, cm 132 136 127 140 3.6 0.347 0.019
 Large intestine weight, g 64 71 64 71 2.8 0.123 0.108
 Large intestine fill, g 56 76 60 72 4.6 0.006 0.082
Weight relative to body weight, %
 Stomach 0.56 0.57 0.54 0.58 0.020 0.726 0.178
 Small intestine 2.71 2.87 2.72 2.86 0.096 0.223 0.334
 Large intestine 0.80 0.92 0.80 0.92 0.035 0.026 0.021
Weight: length ratio, g/cm
 Small intestine (SI) 0.30 0.29 0.30 0.28 0.011 0.657 0.201
 Large intestine 0.50 0.52 0.51 0.51 0.021 0.480 0.910
SI permeability, log10 mg/L b
 Proximal (PB) 1.18 1.05 1.14 1.09 0.074 0.246 0.699
 Proximal (Co) 1.97 1.87 1.94 1.90 0.054 0.219 0.631
 Distal (PB) 0.99 0.99 0.97 1.02 0.069 0.855 0.587
 Distal (Co) 1.84 1.83 1.82 1.85 0.045 0.896 0.557

aExcluding the gut sections used for the everted sac procedure

bData are log10 transformed concentrations of Patent Blue (PB) and cobalt (Co) in the everted sac section