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. 2019 Oct 15;19:267. doi: 10.1186/s12935-019-0985-9

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — CircPVT1 was up-regulated in EC. a The circPVT1 expression level in blood samples was detected and there is no significant difference between EC patients and healthy people. P > 0.05; n = 20. b The circPVT1 was markedly up-regulated in EC tissues compared with the adjacent tissues. **P < 0.01; n = 20. c The level of circPVT1 was significantly increased in cancer cell lines, especially in EC109, TE-1 and TE-10. **P < 0.01; n = 3. d The circPVT1 levels decreased significantly when TE-1 cells were maintained to over-confluence. P < 0.01; n = 3. e The circPVT1 levels decreased significantly when EC109 cells were maintained to over-confluence. P < 0.01; n = 3. f The circPVT1 levels decreased significantly when TE-10 cells were maintained to over-confluence. P < 0.01; n = 3