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Silencing circ-PVT1 subsequently decreased cell survival. A The target of siRNAs were circPVT1 specifically. B The expression of circPVT1 was substantially decreased 48 h after treated with siRNA. **P < 0.01; n = 3. C The expression of linear PVT1 was not affect with siRNA. P > 0.05;n = 3. D–G The Hoechst staining of TE-10 cells. H The apoptotic cells were increased significantly after siRNA transfection to the TE-10 cells. P < 0.01; n = 3
