Table 1.
Patient | Age | Sex | Underlying disease | Prior doxorubicin dose (mg/m2) | Cumulative PLD dose (mg/m2) | Billingham score | Reference |
---|---|---|---|---|---|---|---|
1 | Unknown | M | KS | 0 | 500 | 1 | [25] |
2 | Unknown | M | KS | 0 | 541 | 0 | [25] |
3 | 35 | F | Breast cancera | 180 | 564 | 0.5 | [26] |
4 | Unknown | M | KS | 0 | 578 | 0 | [25] |
5 | Unknown | M | KS | 0 | 610 | 0.5 | [25] |
6 | 54 | F | Breast cancera | 0 | 675 | 0.5 | [27] |
7 | 47 | F | Breast cancera | 0 | 685 | 0 | [26] |
8 | 66 | F | Ovarian cancer | 0 | 730 | 0 | [26] |
9 | Unknown | M | KS | 0 | 780 | 0 | [25] |
10 | Unknown | M | KS | 0 | 801 | 0.5 | [25] |
11 | Unknown | M | KS | 0 | 860 | 0 | [25] |
12 | 36 | F | Ovarian cancer | 375 | 952 | 0 | [26] |
13 | 52 | F | Breast cancera | 360 | 1320 | 1.5 | [26] |
14 | 49 | F | Breast cancer | 0 | 1485 | 1 | [26] |
Abbreviations: M Male, F Female, KS Kaposi sarcoma, PLD Pegylated liposomal doxorubicin
aPatients 3, 6, 7, and 13 received prior radiotherapy to the breast