Table 5.
Multivariable logistic and linear regression models of the secondary endpoints according to the mineral metabolite levels in all 158 patients with AKI
| Biomarker | RRT/Death | Hospital-free days | Ventilator-free days | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | β (SEM) | P value | β (SEM) | P value | |
| Calcium (mmol/L) | 5.57 (0.66, 47.32) | 0.111 | −3.19 (2.54) | 0.203 | −1.45 (3.62) | 0.721 |
| Phosphate (mmol/L) | 0.94 (0.42, 2.10) | 0.973 | −0.66 (1.09) | 0.580 | −0.46 (1.55) | 0.852 |
| iPTH (ng/dL) | 1.00 (0.97, 1.04) | 0.935 | −0.05 (0.06) | 0.388 | −0.16 (0.08) | 0.031 |
| 25D (ng/mL) | 0.97 (0.90, 1.04) | 0.355 | −0.16 (0.08) | 0.050 | −0.13 (0.12) | 0.288 |
| BAP (μg/L) | 1.07 (1.00, 1.16) | 0.073 | −0.30 (0.09) | < 0.001 | −0.27 (0.13) | 0.027 |
| TRACP-5b (U/L) | 1.21 (0.77, 1.92) | 0.413 | −0.13 (0.54) | 0.819 | −1.07 (0.76) | 0.148 |
| cFGF23 (RU/μL) | 1.47 (1.06, 2.05) | 0.029 | −0.95 (0.26) | < 0.001 | −1.68 (0.37) | < 0.001 |
AKI acute kidney injury, RRT/death renal replacement therapy or in-hospital mortality, iPTH intact parathyroid hormone, 25D 25-hydroxyvitamin D, BAP bone-specific alkaline phosphatase, TRACP-5b tartrate-resistant acid phosphatase 5b, cFGF23 C-terminal fibroblast growth factor 23