Table 6.
Clinical characteristics and clinical outcomes of all patients hospitalized with community-acquired pneumonia (CAP) and patients with severe CAP
| All Patients | Severe CAP | |||||
|---|---|---|---|---|---|---|
| Favorable Outcome† (n = 63) |
Unfavorable Outcome† (n = 31) |
p-value | Favorable Outcome† (n = 25) |
Unfavorable Outcome† (n = 25) |
p-value | |
| Age, y | 65.6 ± 18.5 | 77.9 ± 11.8 | <.001* | 65.5 ± 15.7 | 76.4 ± 11.7 | .008* |
| Gender (Female) | 25 (39.7) | 12 (38.7) | .93 | 9 (36) | 9 (36) | 1 |
| Comorbid conditions: | .04* | .65 | ||||
| None | 22 (34.9) | 4 (12.9) | 6 (24) | 3 (12) | ||
| Single | 25 (39.7) | 13 (41.9) | 10 (40) | 11 (44) | ||
| Multiple | 16 (25.4) | 14 (45.2) | 9 (36) | 11 (44) | ||
| Prior antibiotic therapya | 29 (46) | 14 (45.2) | .94 | 10 (40) | 11 (44) | .77 |
| ECOG ≥2b | 31 (49.2) | 23 (74.2) | .02* | 11 (44) | 7 (28) | .24 |
| Enteral tube feeding | 5 (7.9) | 4 (12.9) | .47 | 3 (12) | 3 (12) | 1 |
| HCAPc | 20 (31.7) | 10 (32.3) | .96 | 11 (44) | 7 (28) | .24 |
| Pleural effusion | 7 (11.1) | 4 (12.9) | 1 | 0 | 3 (12) | .23 |
| Albumin, g/dL | 3 ± 0.5 | 2.9 ± 0.6 | .24 | 2.9 ± 0.5 | 2.8 ± 0.7 | .84 |
| Globulin, g/dL | 3.9 ± 0.6 | 3.7 ± 0.9 | .26 | 3.7 ± 0.6 | 3.6 ± 1 | .79 |
Data are presented as mean ± SD or n (%), unless otherwise stated. †Unfavorable outcome includes treatment failure or death during hospital admission. aPrior antibiotic therapy: systemic antibiotic use in the 90 days prior to this admission. bECOG scale: Eastern Cooperative Oncology Group scale of performance status
cHCAP: healthcare–associated pneumonia. *Statistically significant difference