Table 2.
H-Score for reactive hemophagocytic syndrome in our patient
| Criteria | Score |
|---|---|
| Know underlying immunosuppression (that is, HIV positive or receiving long-term immunosuppressive therapy, such as glucocorticoids, cyclosporine, and azathioprine | Yes (+ 18 points) |
| Temperature (°C) | 39.5 °C (+ 49 points) |
| Organomegaly | No (0) |
| Number of cytopenia (defined as hemoglobin ≤ 9.2 g/dl and/or WBC ≤ 5000/mm3 and/or platelets ≤ 110,000/mm3) | 2 lineages (+ 24 points) |
| Ferritin (ng/ml) | 1778 (0) |
| Triglyceride (mg/dl) | 195 (+ 44) |
| Fibrinogen (g/l) | 2 (30) |
| AST (U/L) | 35 (+ 19 points) |
| Hemophagocytosis features on bone marrow aspirate | Yes (+ 35 points) |
| Total | 219 points |
Probability of hemophagocytic syndrome in our patient is 93–96%. Optimal cut-off 169 points. AST aspartate transferase, WBC white blood cell, HIV human immunodeficiency virus