Table 1.

Differentially regulated cytoskeletal proteins upon dTau deletion

Gene	Identifier	Log 2 fold change	p Value
tau	FBgn0266579	−7.66922013	0*
futsch	FBgn0259108	−0.098929167	0.23816
Map205	FBgn0002645	0.172052622	0.163753
Map60	FBgn0010342	0.447441737	0.012972*
Jupiter	FBgn0051363	−0.281016827	0.013477*
ens	FBgn0264693	−0.176790555	0.411188
Mapmodulin	FBgn0034282	0.385273457	0.00035*
βTub56D	FBgn0003887	−0.467973868	0.000265*
βTub97EF	FBgn0003890	−0,399647633	0.004722*
αTub84D	FBgn0003885	−0.209974686	0.01011*
HDAC6	FBgn0026428	−0.393520594	0.014513*
Dhc64C	FBgn0261797	0.173733711	0.00421*
Dlic	FBgn0030276	0.268746932	0.001894*
BicD	FBgn0000183	0.389154911	0.013152*
Klc	FBgn0010235	0.258972645	0.008748*
Khc	FBgn0001308	0.284088135	0.000915*
Klp10A	FBgn0030268	0.30295078	0.000371*
Mtor	FBgn0013756	0.234465	0.000624*
CLIP-190	FBgn0020503	0.197493394	0.001698*
shot	FBgn0013733	0.026000439	0.729461
Actin-5C	FBgn0000042	0.101068815	0.097274
Arm	FBgn0000117	0.287528	0.005765*
α-Cat	FBgn0010215	0.194383144	0.008364*
sqh	FBgn0003514	0.302096923	0.011639*
sn	FBgn0003447	0.478138049	0.000003*
cpb	FBgn0011570	0.188986699	0.013467*
tsr	FBgn0011726	0.160349607	0.000611*
cpa	FBgn0034577	0.211062511	0.00578*
zip	FBgn0265434	0.229537	0.018528*
vib	FBgn0267975	−0.180737	0.015157*
flr	FBgn0260049	0.207514842	0.000992*
Lam	FBgn0002525	0.170005878	0.016684*

Selected proteins, p values, and average log2 fold differences from three biological and two technical replicas have been calculated as described in Materials and Methods. The log2 fold change becomes positive when mutant > control and negative when control > mutant. The t test was performed with a permutation-based FDR (0.05) calculation, and the p value determines the statistical significance (*p < 0.05). Proteins are functionally grouped into Drosophila MAP family proteins, tubulin and microtubule-associated proteins, actin, and actin associated proteins.