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. 2019 Oct 16;39(42):8362–8375. doi: 10.1523/JNEUROSCI.2422-18.2019

Figure 5.

Figure 5.

FA mediation shown are axial brain images of FA mediating the associations of age with psychometric scores; FA correlations with age are shown at the top for ease of reference. A, Findings in the 9- to 12-year-old cohort; B, findings in the 5- to 14-year-old cohort. FDR correction for multiple comparisons was applied with FDR at p < 0.01. Significant positive correlations (p < 0.01) are indicated by warm colors (red, orange), and significant inverse correlations are shown as cool colors (shades of blue). Significant FA mediations of age were seen with Design Copy Process Global and Hit Reaction Time scores, most notably in the lenticular nucleus, thalamus, caudate, posterior limb of the internal capsule, corpus callosum and inferior fronto-occipital fasciculus. ALIC, Anterior limb of internal capsule; Cb, cerebellum; CCsp, splenium of corpus callosum; Cd, caudate; CR, corona radiata; IFG, inferior frontal gyrus; Ins, insular cortex; LN, lenticular nucleus; Mb, midbrain; mOCC, medial occipital cortex; MTG, middle temporal gyrus; OFG, orbitofrontal gyrus; PCC, posterior cingulate cortex; PLIC, posterior limb of internal capsule; Put, putamen; SFOF, superior fronto-occipital fasciculus; SMG, supramarginal gyrus; STG, superior temporal gyrus; Th, thalamus.