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Vaccines target the life cycle of Plasmodium falciparum. (a) Pre-erythrocytic Plasmodium vaccine: vaccine produces antibodies that kill infected liver cells or interfere with the malaria parasite during liver cell proliferation; (b) asexual blood-stage vaccine: vaccine aims primarily at reducing parasite load or eliminating circulating parasites; (c) vaccine aims at controlling the transmission of malaria parasites from human hosts to the mosquito vectors.
