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. 2019 Nov;25(11):1439–1456. doi: 10.1261/rna.071944.119

FIGURE 4.

FIGURE 4.

Radial distribution function of Na+ ions about the O6 (top plot) and N7 (bottom plot) atoms of G40 in its active state (blue) and native protonation state (black), compared to the average radial distribution function for the other 15 guanines in the 5K7C ribozyme (red), with the standard deviation shaded in pink. The average coordination number of the first Na+ ion shell about the O6 is 1.0 for G40, 0.8 for G40, and 0.3 for Other G. The coordination number of the first sodium shell about the N7 is 0.7 for G40−, 0.4 for G40, and 0.2 for Other G.